{"id":5670,"date":"2024-05-16T08:35:00","date_gmt":"2024-05-16T05:35:00","guid":{"rendered":"https:\/\/new.webcozumleri.com\/?p=5670"},"modified":"2025-03-27T18:15:53","modified_gmt":"2025-03-27T15:15:53","slug":"pine-bark","status":"publish","type":"post","link":"https:\/\/new.webcozumleri.com\/en\/pine-bark\/","title":{"rendered":"Pine Bark"},"content":{"rendered":"<blockquote><p><em><strong>More than 100 different species of pine trees exist. They\u2019re an ancient genus of evergreen trees that grow abundantly in many parts of the northern hemisphere and in some parts of the southern hemisphere as well.\u00a0In the past, many cultures have used the bark, needles, resin, and nuts of pine trees as medicine (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29651231\/\" target=\"_blank\" rel=\"noopener\">1<\/a>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25597308\/\" target=\"_blank\" rel=\"noopener\">2<\/a>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26784337\/\" target=\"_blank\" rel=\"noopener\">3<\/a>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21535752\/\" target=\"_blank\" rel=\"noopener\">4<\/a>).<\/strong><\/em><\/p><\/blockquote>\n<p><span style=\"font-weight: 400;\">In the 1940s, scientist Jacques Masquelier began studying the health effects of pine bark after learning that indigenous peoples of North America were using pine bark tea to heal scurvy and wounds (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29651231\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">1<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28103873\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">5<\/span><\/a><span style=\"font-weight: 400;\">). <\/span><span style=\"font-weight: 400;\">Since then, pine bark extract has continued to increase in popularity as an herbal supplement. <\/span><span style=\"font-weight: 400;\">This article explains what pine bark extract is, what it\u2019s used for, and how to use it safely.<\/span><\/p>\n<h2><b>What is it?<\/b><\/h2>\n<p><i><span style=\"font-weight: 400;\">Pinus pinaster<\/span><\/i><span style=\"font-weight: 400;\"> is a type of pine tree native to areas of the Mediterranean including Portugal, Spain, France, and Morocco. The trees are commonly called maritime or cluster pines.\u00a0<\/span><span style=\"font-weight: 400;\">The bark of maritime pines is thick and grows in various shades of brown, orange, and red.\u00a0 <\/span><span style=\"font-weight: 400;\">Although many species of pine appear to have beneficial health properties, the majority of pine bark extracts sold as herbal supplements today come from maritime pines (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25597308\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">2<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26784337\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">3<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21888955\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">6<\/span><\/a><span style=\"font-weight: 400;\">).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Pine bark extract is sold under a variety of trade names with some of the most common being:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pycnogenol<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Oligopin<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Flavangenol<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Sometimes these supplements contain other ingredients in addition to the bark, such as:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">vitamin C<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">other plant extracts<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">fillers like cellulose or glycerin<\/span><\/li>\n<\/ul>\n<h2><b>How it\u2019s Made?<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Maritime pine bark extract is made by first grinding pine bark, then washing and soaking it in hot water. Next, the solids are removed from the liquid extract (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25597308\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">2<\/span><\/a><span style=\"font-weight: 400;\">). <\/span><span style=\"font-weight: 400;\">The liquid extract can then be used as is or further processed by freeze-drying and grinding it into a powder.<\/span><\/p>\n<h2><b>What Makes Pine Bark Effective?<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Maritime pines are known to contain health-promoting plant compounds like vitamins,\u00a0<\/span><span style=\"font-weight: 400;\">polyphenols<\/span><span style=\"font-weight: 400;\">, and other phytonutrients.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Many of these are also found in other supplements like grape seed and witch hazel extracts (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28103873\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">5<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/medlineplus.gov\/druginfo\/natural\/1019.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">7<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29725583\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">8<\/span><\/a><span style=\"font-weight: 400;\">).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The total amount of compounds in pine bark extract may vary depending on the type of bark used and how it was manufactured (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32325962\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">9<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32048960\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">10<\/span><\/a><span style=\"font-weight: 400;\">).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The following is a brief summary of the most notable polyphenol nutrients in pine bark extract and how they may benefit human health:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Procyanidins.<\/b><span style=\"font-weight: 400;\">\u00a0A type of flavonoid that acts as an antioxidant and appears to have medicinal properties. All Pycnogenol maritime pine bark extract is standardized to contain at least 75% procyanidins (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29725583\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">8<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33045354\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">11<\/span><\/a><span style=\"font-weight: 400;\">,<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30215292\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">12<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29462565\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">13<\/span><\/a><span style=\"font-weight: 400;\">).<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Catechins.<\/b><span style=\"font-weight: 400;\">\u00a0Another antioxidant-like flavonoid family that protects cells from oxidation and damaging free radicals (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28103873\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">5<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29725583\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">8<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32325962\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">9<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30215292\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">12<\/span><\/a><span style=\"font-weight: 400;\">).<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Phenolic acids.<\/b><span style=\"font-weight: 400;\">\u00a0A group of polyphenols that exhibit high antioxidant activity and are commonly found in plant foods (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25597308\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">2<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32325962\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">9<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29462565\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">13<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31516850\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">14<\/span><\/a><span style=\"font-weight: 400;\">).<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">These compounds are believed to be what makes pine bark useful as an herbal supplement, giving it the following effects:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">antioxidant (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32325962\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">9<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30803506\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">15<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23867543\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">16<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22036974\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">17<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">antimicrobial (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32325962\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">9<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31958081\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">18<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29962429\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">19<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28448268\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">20<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">anti-inflammatory (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25597308\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">2<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30215292\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">12<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30803506\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">15<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30678156\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">21<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">It\u2019s thought that the extract\u2019s antioxidant, antimicrobial, and anti-inflammatory properties have the potential to improve conditions like cancer, heart disease, and neurodegenerative conditions like Alzheimer\u2019s disease \u2014 but more research is needed (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25597308\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">2<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30803506\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">15<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31958081\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">18<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0924224418301341\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">22<\/span><\/a><span style=\"font-weight: 400;\">).<\/span><\/p>\n<h2><b>Does it Have Benefits?<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Test-tube and animal studies from the past few decades have found encouraging results to support the health-promoting benefits of pine bark extract.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Many studies have been conducted on the trademark brand of French maritime pine bark extract known as Pycnogenol. Due to its anti-inflammatory effects, researchers are beginning to investigate it as a possible therapeutic option for the\u00a0<\/span><span style=\"font-weight: 400;\">novel coronavirus (SARS-CoV-2)<\/span><span style=\"font-weight: 400;\">, which causes the disease COVID-19 (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33045354\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">11<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30215292\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">12<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22049273\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">23<\/span><\/a><span style=\"font-weight: 400;\">). <\/span><span style=\"font-weight: 400;\">Still, rigorous research on the effectiveness of pine bark extract in humans is lacking, and more randomized controlled-trial studies are needed. So, it\u2019s too soon to say how safe and effective pine bark extracts are for treating specific illnesses (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32990945\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">24<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22513958\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">25<\/span><\/a><span style=\"font-weight: 400;\">). <\/span><span style=\"font-weight: 400;\">As more research is conducted, we\u2019ll gain a better understanding of the best ways to use pine bark extract. <\/span><span style=\"font-weight: 400;\">Nevertheless, the extract continues to show potential. Here are some of the initial benefits of pine bark extract purported today.<\/span><\/p>\n<h2><b>May Reduce Inflammation<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">It appears that French maritime pine bark exerts much of its anti-inflammatory capabilities by influencing your body\u2019s cellular pathways that regulate inflammation and your\u00a0<\/span><span style=\"font-weight: 400;\">immune system<\/span> <span style=\"font-weight: 400;\">(<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30678156\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">21<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22049273\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">23<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27725237\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">26<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27643741\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">27<\/span><\/a><span style=\"font-weight: 400;\">). <\/span><span style=\"font-weight: 400;\">Researchers are still investigating how this could benefit conditions like chronic heart disease, diabetes, traumatic brain injuries, and more (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32046747\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">28<\/span><\/a><span style=\"font-weight: 400;\">). <\/span><span style=\"font-weight: 400;\">The apparent ability of pine bark to alleviate inflammation has also led to studies on its potential as a therapeutic treatment for chronic airway inflammation conditions, like asthma and chronic obstructive pulmonary disease (COPD) (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27725237\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">26<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27643741\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">27<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20640388\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">29<\/span><\/a><span style=\"font-weight: 400;\">).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For example, animal and test-tube studies have shown positive results for Pyconogenol\u2019s ability to improve inflammation in airway cells (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27725237\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">26<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27643741\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">27<\/span><\/a><span style=\"font-weight: 400;\">,<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24120901\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">30<\/span><\/a><span style=\"font-weight: 400;\">). <\/span><span style=\"font-weight: 400;\">A few older studies including humans found similar effects of Pycnogenol\u2019s ability to alleviate asthma symptoms \u2014 though these studies were too small to make definitive conclusions about pine bark\u2019s effectiveness as an herbal supplement (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22108478\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">31<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15641632\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">32<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12639402\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">33<\/span><\/a><span style=\"font-weight: 400;\">). <\/span><span style=\"font-weight: 400;\">One study including 76 asthma patients found that taking 100 milligrams of Pycnogenol daily for 6 months, in combination with inhaled corticosteroid medications, significantly improved coughing and wheezing and decreased dependency on the corticosteroids (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22108478\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">31<\/span><\/a><span style=\"font-weight: 400;\">).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Further, human and animal studies have found that procyanidin-rich pine bark extracts may ease short- and long-term bone and joint inflammation associated with arthritis. However, larger randomized controlled trials are needed to confirm these findings (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28836883\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">34<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29246219\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">35<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28452960\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">36<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27941690\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">37<\/span><\/a><span style=\"font-weight: 400;\">).<\/span><\/p>\n<h2><b>May Support Heart Health<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Because pine bark is both anti-inflammatory and antioxidant-like, it may support a healthy\u00a0<\/span><a href=\"https:\/\/www.healthline.com\/health\/fun-facts-about-the-heart\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">heart<\/span><\/a> <span style=\"font-weight: 400;\">and cardiovascular system in a number of ways (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30456865\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">38<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29096743\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">39<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21436602\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">40<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27322603\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">41<\/span><\/a><span style=\"font-weight: 400;\">). <\/span><span style=\"font-weight: 400;\">These include limiting the buildup of fat, reducing oxidative stress and the likelihood of blood clots, and improving venous function (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25458248\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">42<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22227333\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">43<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21607011\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">44<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21069260\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">45<\/span><\/a><span style=\"font-weight: 400;\">). <\/span><span style=\"font-weight: 400;\">Plus, it\u2019s possible that pine bark may offset certain negative side effects of chronic diseases like diabetes and metabolic syndrome (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25931421\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">46<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30465898\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">47<\/span><\/a><span style=\"font-weight: 400;\">). <\/span><span style=\"font-weight: 400;\">One small 2016 study including 24 adults with high blood pressure found that taking 150 milligrams Oligopin pine bark daily for 5 weeks improved HDL (good) cholesterol measures and lowered systolic blood pressure by an average of 6.36 mmHg (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27765365\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">48<\/span><\/a><span style=\"font-weight: 400;\">). <\/span><span style=\"font-weight: 400;\">Another small 2012 study including 23 adults with coronary heart disease associated taking 200 mg of Pycnogenol per day with improved blood flow through the arteries and lower levels of isoprostane \u2014 a measure of oxidative stress. No changes to blood pressure were noted (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22240497\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">49<\/span><\/a><span style=\"font-weight: 400;\">).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Meta-analysis studies on Pycnogenol and blood pressure have found similar results (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31637782\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">50<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31585179\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">51<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30087862\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">52<\/span><\/a><span style=\"font-weight: 400;\">). <\/span><span style=\"font-weight: 400;\">Meanwhile, other studies have found pine bark extract to be less effective at reducing heart disease risk (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24346156\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">53<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20876405\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">54<\/span><\/a><span style=\"font-weight: 400;\">). <\/span><span style=\"font-weight: 400;\">Recent meta-analysis studies have determined that there\u2019s not enough evidence to support a link between Pycnogenol and blood pressure (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31763928\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">55<\/span><\/a><span style=\"font-weight: 400;\">).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">So, although pine bark extract appears to support the mechanisms of heart health, it\u2019s still unclear how safe and effective it is as a treatment for specific conditions.<\/span><\/p>\n<h2><b>Other Potential Uses<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Pine bark extracts are also being investigated for a multitude of other uses in human, animal, and test-tube studies. These include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">healthy aging (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30215292\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">12<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31333448\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">56<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">wound healing (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28448268\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">20<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23444785\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">57<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">menopause\u00a0<\/span><span style=\"font-weight: 400;\">(<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28116886\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">58<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23447917\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">59<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22108479\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">60<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">bone loss (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33250314\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">61<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30907034\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">62<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25336411\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">63<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21710590\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">64<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Alzheimer\u2019s disease (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31958081\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">18<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30668321\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">65<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">attention deficit hyperactivity disorder (ADHD) (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28137522\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">66<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21827936\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">67<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">skin health (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32046246\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">68<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32841433\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">69<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22270036\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">70<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22956863\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">71<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">athletic performance (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24247188\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">72<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">improved cognition (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29754480\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">73<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26635191\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">74<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24675223\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">75<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22108481\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">76<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">erectile dysfunction (<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31855055\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">77<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26428638\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">78<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25664962\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">79<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21618639\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">80<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>More than 100 different species of pine trees exist. They\u2019re an ancient genus of evergreen trees that grow abundantly in many parts of the northern&#8230;<\/p>\n","protected":false},"author":11,"featured_media":9822,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[142],"tags":[],"class_list":["post-5670","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-plant-index"],"acf":[],"_links":{"self":[{"href":"https:\/\/new.webcozumleri.com\/en\/wp-json\/wp\/v2\/posts\/5670","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/new.webcozumleri.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/new.webcozumleri.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/new.webcozumleri.com\/en\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/new.webcozumleri.com\/en\/wp-json\/wp\/v2\/comments?post=5670"}],"version-history":[{"count":6,"href":"https:\/\/new.webcozumleri.com\/en\/wp-json\/wp\/v2\/posts\/5670\/revisions"}],"predecessor-version":[{"id":8259,"href":"https:\/\/new.webcozumleri.com\/en\/wp-json\/wp\/v2\/posts\/5670\/revisions\/8259"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/new.webcozumleri.com\/en\/wp-json\/wp\/v2\/media\/9822"}],"wp:attachment":[{"href":"https:\/\/new.webcozumleri.com\/en\/wp-json\/wp\/v2\/media?parent=5670"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/new.webcozumleri.com\/en\/wp-json\/wp\/v2\/categories?post=5670"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/new.webcozumleri.com\/en\/wp-json\/wp\/v2\/tags?post=5670"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}